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  • 产品名称： Research Grade Tocilizumab ( 托珠单抗 )
  • 产品货号： CSD00661
  • 货期： 现货
  • 价格与订购： 2480
  • 数量：
    库存： 10
  • 规格： 100μg
  • 产品信息
  • 如何订购
    货号（Catalog No.）
    CSD00661
    通用名INN
    Tocilizumab
    纯度(Purity)
    >95%
    浓度( Concentration)
    1mg/ml
    Formulation
    PBS buffer PH7.5
    Source
    CHO cells
    内毒素(Endotoxin level)
    Please contact with the lab for this information.
    产品描述(Description)
    Tocilizumab (Anti-Human IL6R, Humanized Antibody) is an anti-human interleukin-6 receptor (IL-6R) neutralizing antibody,prevents binding of IL-6 to the IL-6R,thereby inhibiting both classic and trans-signaling.Tocilizumab (Anti-Human IL6R, Humanized Antibody) can be used for the treatment of rheumatoid arthritis.
    别名(Alternative names)
    Atlizumab,MRA/R-1569/RHPM-1/RO-4877533
    靶点;物种(Specificity target name;species)
    IL-6R
    活性研究（体外/体内研究）(Activity in vitro)
    Tocilizumab (Anti-Human IL6R, Humanized Antibody) (1-100 ng/mL; 24 hours, 48 hours) inhibits the cell proliferation (growth rate) in a dose-dependent manner, growth rate by HACM is reduced almost completely by 100 ng/mL tocilizumab.
    Tocilizumab (Anti-Human IL6R, Humanized Antibody) (0.001-10,000 μg/ml; 2 days) inhibits Ba/F3-gp130-IL-6R cell proliferation stimulated with hIL-6 with an IC50 of 13.5 ng/ml.
    Tocilizumab (Anti-Human IL6R, Humanized Antibody) (1 μM; 6 hours) reduces the phosphorylation of STAT3 in vitro consistent with in vivo SAS cells.
    Tocilizumab (Anti-Human IL6R, Humanized Antibody) (1-5 μM; 24 hours) significantly reduces VEGF mRNA expression in SAS cells with serum-free medium.
    受体鉴定(Receptor identification)
    IgG1
    CAS
    375823-41-9
    存储条件(Storage)
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Store at +4°C short term (1-2 weeks).
    Store at -20 °C 12 months.
    Store at -80°C long term.
    Note
    For research use only .
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