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  • 产品名称： Research Grade Ruplizumab ( 卢利珠单抗 )
  • 产品货号： CSD00002
  • 货期： 现货
  • 价格与订购： 2480
  • 数量：
    库存： 100
  • 规格： 100μg
  • 产品信息
  • 如何订购
    货号（Catalog No.）
    CSD00002
    通用名INN
    Ruplizumab
    纯度(Purity)
    >95%
    浓度( Concentration)
    1mg/ml
    Formulation
    PBS buffer PH7.5
    Source
    CHO cells
    内毒素(Endotoxin level)
    Please contact with the lab for this information.
    产品描述(Description)
    Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.Ruplizumab is an anti-CD40L monoclonal antibody.The binding of CD40 to its ligand,CD40L is a critical element in T cell activation.In systemic lupus erythematosus,CD40L is over-expressed on T cells, B cells and monocytes.
    别名(Alternative names)
    BG-9588,hu5c8
    靶点;物种(Specificity target name;species)
    CD40LG[Homo sapiens]
    靶点背景信息(Target information)
    Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
    种类(Species)
    Humanized
    受体鉴定(Receptor identification)
    IgG1-kappa
    分子量(MV)
    145448.00 Da
    CAS
    220651-94-5
    存储条件(Storage)
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Store at +4°C short term (1-2 weeks).
    Store at -20 °C 12 months.
    Store at -80°C long term.
    Note
    For research use only .
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